Interactor 1: CDC20 (P26309)
APC/C activator protein CDC20 (Cell division control protein 20)
Gene: CDC20
Interactor 2: MAD3 (P47074)
Spindle assembly checkpoint component MAD3 (Mitotic MAD3 protein)
Gene: MAD3
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10704439, 10848588, 11805837, 17369399, 17406666, 9461437, 28189585, 31928870, 15879521, 11726501, 14660704 |
| Identification Methods | coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Mad3_BUB1_I~WD40, Mad3_BUB1_II~WD40 |
| Common GO terms | GO:0005634 - nucleus GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0033597 - mitotic checkpoint complex GO:0051301 - cell division |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
