HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: AL3A2 (P51648)
Aldehyde dehydrogenase family 3 member A2 (EC 1.2.1.3) (EC 1.2.1.94) (Aldehyde dehydrogenase 10) (Fatty aldehyde dehydrogenase) (Microsomal aldehyde dehydrogenase)
Gene: ALDH3A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007422 - peripheral nervous system development
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 485
+	Hs
		410722 ERBB2_HUMAN (25-1222): 0: 1075: 39.95		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		362998 EGFR_HUMAN (18-1211): 0: 1060: 40.65		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		362935 EGFR_HUMAN (18-1211): 0: 1060: 40.65		AL3B1_HUMAN (3-458): 1.35e-167: 482: 53.73
+	Hs
		463928 RET_HUMAN (518-1072): 5.32e-118: 397: 21.15		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		906041 ROR2_HUMAN (491-1088): 8.52e-118: 393: 20.22		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		465462 IGF1R_HUMAN (330-644): 8.95e-24: 111: 21.34		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		439686 INSR_HUMAN (330-650): 2.92e-23: 109: 17.30		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Hs
		572913 INSRR_HUMAN (330-644): 1.2e-16: 88.3: 14.55		AL3A2_HUMAN (1-485): 0: 524: 100.00
+	Rn
		108244 INSR_RAT (330-650): 1.67e-21: 104: 17.89		G3V9W6_RAT (1-464): 4.87e-170: 492: 85.99