HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	26641092, 22365833
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 305
+	Hs
		609718 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609883 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609833 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609862 ELAV3_HUMAN (127-472): 9.26e-67: 220: 13.98		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		641756 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		516364 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		453159 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		1031344 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		641676 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		1020249 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		516484 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		201670 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56
+	Hs
		641770 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		453381 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		852068 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		1077450 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		1048074 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		162059 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Zm
		8143 A0A1D6ELH4_MAIZE (87-419): 6.02e-48: 176: 15.27		A0A1D6ELH4_MAIZE (2-297): 3.82e-18: 86.6: 14.82
+	Hs
		162048 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91