Protein: SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)

Gene: SDHB, SDH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P21801

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
GO:0008177 - succinate dehydrogenase (quinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641106

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

4

7

Small-scale

0.873

High

641094

DHSD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

3

0

Small-scale

0.784

High

392228

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.675

High

578846

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.618

High

641090

SDH3
Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial

1

1

High-throughput

0.618

High

641101

SDHX
Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial

1

7

High-throughput

0.618

High

613519

ADT2
ADP,ATP carrier protein 2

2

2

Small-scale

0.611

High

510193

HSP77
Import motor subunit, mitochondrial

2

5

High-throughput

0.584

High

641113

SDHF1
Succinate dehydrogenase assembly factor 1, mitochondrial

2

1

Small-scale

0.584

High

641095

TCM62
Mitochondrial chaperone TCM62

1

7

Small-scale

0.561

High

641087

NFU1
NifU-like protein, mitochondrial

2

0

Small-scale

0.559

High

641092

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

641111

FRDA
Frataxin homolog, mitochondrial

1

1

Small-scale

0.515

High

470100

SPS1
Sporulation-specific protein 1

1

1

High-throughput

0.489

High

453107

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.479

High

453247

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.479

High

484721

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

598307

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.479

High

604899

MDHM
Malate dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

641085

ACPM
Acyl carrier protein, mitochondrial

1

1

High-throughput

0.479

High

641086

ZUO1
Zuotin

1

1

Small-scale

0.479

High

641089

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

641093

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

641100

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

2

High-throughput

0.479

High

641108

SDHF3
Succinate dehydrogenase assembly factor 3, mitochondrial

1

1

Small-scale

0.479

High

641109

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

641112

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

360867

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

0

High-throughput

0.458

High

431979

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

452812

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

637313

ATP5E
ATP synthase subunit epsilon, mitochondrial

1

0

High-throughput

0.458

High

641083

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

641088

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

641091

MCR1
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.458

High

641096

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

641097

BOL3
BolA-like protein 3

1

0

Small-scale

0.458

High

641098

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

641103

AIM24
Altered inheritance of mitochondria protein 24, mitochondrial

1

0

High-throughput

0.458

High

641104

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

641105

ATP18
ATP synthase subunit J, mitochondrial

1

0

High-throughput

0.458

High

641084

HS104
Heat shock protein 104

1

1

High-throughput

0.407

High

509395

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

523059

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.249

Low

641102

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

641110

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

641107

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

641099

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025