HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17589525
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 401
+	Mm
		857354 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		SPF45_MOUSE (1-401): 3.28e-154: 442: 98.27
+	Hs
		641773 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054340 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1020258 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Dm
		1370583 Q9VM49_DROME (16-470): 2.22e-72: 241: 18.36		Q9VM49_DROME (81-394): 1.42e-65: 220: 14.07
+	Hs
		1054312 ELAV3_HUMAN (127-472): 9.26e-67: 220: 13.98		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641620 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		641967 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		1054309 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641802 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Dm
		1370590 Q9VYI0_DROME (242-468): 2.17e-30: 123: 19.43		Q9VM49_DROME (81-394): 1.42e-65: 220: 14.07
+	Hs
		1031328 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054653 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Mm
		641996 TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70		U2AF2_MOUSE (244-397): 2.5e-36: 140: 23.93
+	Hs
		1355613 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		641756 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1031490 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67