HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: LMTK3 (Q96Q04)
Serine/threonine-protein kinase LMTK3 (EC 2.7.11.1) (Lemur tyrosine kinase 3)
Gene: LMTK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 1460
+	Hs
		996842 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		LMTK3_HUMAN (1-1460): 0: 925: 100.00
+	Hs
		996757 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		LMTK2_HUMAN (15-1451): 0: 728: 26.65
+	Hs
		959089 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		TNIK_HUMAN (113-1160): 1.11e-136: 457: 12.41
+	Hs
		601460 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		FGFR2_HUMAN (2-471): 1.02e-125: 413: 21.64
+	Hs
		601495 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		FGFR2_HUMAN (2-471): 1.02e-125: 413: 21.64
+	Hs
		665580 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		EPHB2_HUMAN (6-461): 2.86e-120: 405: 21.46
+	Hs
		818072 SOX2_HUMAN (3-94): 2.29e-23: 96.7: 22.83		EPHA7_HUMAN (2-461): 3.7e-117: 395: 20.42
+	Hs
		674397 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		UFO_HUMAN (37-519): 4.72e-107: 364: 24.14
+	Hs
		178911 TOX3_HUMAN (91-165): 3.31e-30: 118: 37.33		LYN_HUMAN (79-423): 6.29e-109: 357: 23.71
+	Hs
		601504 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		FGFR2_HUMAN (2-471): 1.02e-125: 413: 21.64
+	Hs
		442873 TOX2_HUMAN (91-142): 1.64e-18: 84.8: 36.54		HCK_HUMAN (79-423): 5.93e-109: 357: 24.86
+	Hs
		384138 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		384301 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		445824 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		ROS1_HUMAN (117-408): 1.38e-33: 144: 33.78
+	Hs
		385375 CIC_HUMAN (3-100): 1.66e-11: 64.7: 22.45		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		384221 UBF1_HUMAN (10-158): 1.47e-09: 58.9: 24.72		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		384722 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		996635 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		MERTK_HUMAN (139-416): 2.2e-32: 139: 34.62