Interactor 1: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Interactor 2: DCP2 (Q8IU60)
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc)
Gene: DCP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 16364915
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000932 - P-body
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006402 - mRNA catabolic process
GO:0043488 - regulation of mRNA stability
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 326
Hs

1 420
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024