Protein: Q9W4I4
Helix loop helix protein 4C, isoform A (IP01307p)

Gene: Q9W4I4, HLH4C
Organism: Drosophila melanogaster
Interactions: 125
UniProt ID: Q9W4I4

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0046983 - protein dimerization activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393701

HMEN
Segmentation polarity homeobox protein engrailed

1

15

High-throughput

0.656

High

560196

ESM7
Enhancer of split m7 protein

1

17

High-throughput

0.656

High

614997

EMC
Protein extra-macrochaetae

1

15

High-throughput

0.656

High

118274

M9NCY1
Lim3, isoform E

1

11

High-throughput

0.621

High

1477954

Q9VJ00
FI01025p

1

12

High-throughput

0.590

High

1379031

Q960J7
LD47616p

2

1

High-throughput

0.543

High

1487238

Q9VVB5
LD46723p

1

3

High-throughput

0.528

High

355865

O96660
Mothers against decapentaplegic homolog

1

1

High-throughput

0.508

High

1202422

Q59E05
Transcription factor Ouib

1

4

High-throughput

0.508

High

1472722

Q9VEF1
Uncharacterized protein

1

2

High-throughput

0.508

High

1476379

Q9VHM7
IP14660p

1

4

High-throughput

0.508

High

1428013

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.486

High

1486127

Q9VTH8
Uncharacterized protein, isoform A

1

0

High-throughput

0.486

High

1490060

X2JIB5
Uncharacterized protein, isoform D

1

5

High-throughput

0.481

High

56480

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

1

High-throughput

0.464

High

235064

NOI
Splicing factor 3A subunit 3

1

2

High-throughput

0.464

High

304581

ARI2
Potential E3 ubiquitin-protein ligase ariadne-2

1

1

High-throughput

0.464

High

450881

LCP2
Larval cuticle protein 2

1

3

High-throughput

0.464

High

1172891

HOOK
Protein hook

1

2

High-throughput

0.464

High

1174818

MERH
Moesin/ezrin/radixin homolog 2

1

4

High-throughput

0.464

High

1192932

YAP1
Transcriptional coactivator yorkie

1

2

High-throughput

0.464

High

1305898

Q8IR26
RING-type E3 ubiquitin transferase

1

4

High-throughput

0.464

High

1343753

Q8SXG7
tRNA selenocysteine-associated protein 1

1

1

High-throughput

0.464

High

1466471

SUB
Kinesin-like protein subito

1

4

High-throughput

0.464

High

1466812

Q9V9Q6
AT16263p

1

3

High-throughput

0.464

High

1466849

Q9V9R6
No mechanoreceptor potential B, isoform C

1

5

High-throughput

0.464

High

1469002

Q9VB81
Cuticular protein 97Eb

1

1

High-throughput

0.464

High

1476169

Q9VHG0
Heterochromatin protein 1e

1

2

High-throughput

0.464

High

1477283

Q9VI83
G patch domain-containing protein 11

1

1

High-throughput

0.464

High

1481862

Q9VML8
GH01721p

1

1

High-throughput

0.464

High

1484746

Q9VR90
Syntaxin 16

1

1

High-throughput

0.464

High

1488052

FRQ2
Frequenin-2

1

2

High-throughput

0.464

High

1489873

Q9W3I9
GH01161p

1

4

High-throughput

0.464

High

1490057

DGT4
Augmin complex subunit dgt4

1

1

High-throughput

0.464

High

1490059

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

1

High-throughput

0.464

High

1490051

Q9W4F9
IP01388p

1

6

High-throughput

0.457

High

1482201

Q9VMX2
LD03394p

1

1

High-throughput

0.451

High

83

A0A021WW64
Uncharacterized protein, isoform G

1

1

High-throughput

0.439

High

58202

A1ZBG4
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

84929

B7Z0R9
Uncharacterized protein, isoform D

1

1

High-throughput

0.439

High

118700

M9NF85
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

122157

M9PHS8
Uncharacterized protein, isoform C

1

1

High-throughput

0.439

High

873656

PP1B
Serine/threonine-protein phosphatase beta isoform

1

3

High-throughput

0.439

High

1070408

Q0IGY6
IP07646p

1

1

High-throughput

0.439

High

1236981

Q6NP71
Lipophorin receptor 1, isoform J

1

3

High-throughput

0.439

High

1269869

Q7KUQ6
Limpet, isoform K

1

4

High-throughput

0.439

High

1303520

Q8IN05
Liquid facets-Related, isoform D

1

1

High-throughput

0.439

High

1304638

Q8IPL4
Lethal

1

1

High-throughput

0.439

High

1378425

Q95TZ7
GH19182p

1

1

High-throughput

0.439

High

1488373

Q9VXP1
RING-type E3 ubiquitin transferase

1

4

High-throughput

0.439

High

1489592

Q9W1I0
TAR DNA-binding protein 43

1

1

High-throughput

0.439

High

58258

A1ZBG6
Uncharacterized protein, isoform C

1

1

High-throughput

0.417

High

1169471

Q1WWA1
IP04010p

1

1

High-throughput

0.417

High

1265712

Q7K3G5
D4, isoform A

1

12

High-throughput

0.417

High

1305311

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

1

High-throughput

0.417

High

1305366

Q8IQG0
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

1343940

Q8SXP8
TAR DNA-binding protein 43

1

1

High-throughput

0.417

High

1344544

Q8SYH8
RE57644p

1

1

High-throughput

0.417

High

1345533

Q8T0U6
Serine/threonine-protein phosphatase

1

2

High-throughput

0.417

High

1467861

Q9VAE4
RE09305p

1

1

High-throughput

0.417

High

1469333

Q9VBN1
Lipophorin receptor 1, isoform G

1

3

High-throughput

0.417

High

1471074

Q9VD13
GH02671p

1

2

High-throughput

0.417

High

1488203

Q9VXE7
SD21513p

1

1

High-throughput

0.417

High

1489236

Q9W053
Zormin, isoform F

1

4

High-throughput

0.417

High

1488520

LSD2
Lipid storage droplets surface-binding protein 2

1

1

High-throughput

0.407

High

51877

A1Z6G9
FI18173p1

1

0

High-throughput

0.265

Low

52008

A1Z6J6
Uncharacterized protein

1

0

High-throughput

0.265

Low

52908

A1Z7G2
MIP13653p

1

0

High-throughput

0.265

Low

195234

O16158
Calcium-binding protein

1

0

High-throughput

0.265

Low

198012

FZO
Transmembrane GTPase fzo

1

0

High-throughput

0.265

Low

232139

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.265

Low

467221

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.265

Low

875517

KARG
Arginine kinase 1

1

0

High-throughput

0.265

Low

1046781

PROD
Proline dehydrogenase 1, mitochondrial

1

0

High-throughput

0.265

Low

1261876

EAF
Ell-associated factor Eaf

1

0

High-throughput

0.265

Low

1262640

Q7JWU2
AT11581p

1

0

High-throughput

0.265

Low

1267495

Q7KMG7
DNA excision repair protein ERCC-1

1

0

High-throughput

0.265

Low

1321274

Q8MSH5
GH23338p

1

0

High-throughput

0.265

Low

1374763

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.265

Low

1375272

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.265

Low

1467597

Q9VAA7
GEO10372p1

1

0

High-throughput

0.265

Low

1469187

Q9VBI0
Pre-rRNA-processing protein TSR2 homolog

1

0

High-throughput

0.265

Low

1469264

Q9VBK2
Kin of rumpel, isoform C

1

0

High-throughput

0.265

Low

1470819

Q9VCV9
FI18835p1

1

0

High-throughput

0.265

Low

1471357

ARCH
Protein archease-like

1

0

High-throughput

0.265

Low

1472261

Q9VE38
GEO07163p1

1

0

High-throughput

0.265

Low

1474592

Q9VGD6
AT28509p

1

0

High-throughput

0.265

Low

1475043

Q9VGP7
Large ribosomal subunit protein mL40

1

0

High-throughput

0.265

Low

1476233

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.265

Low

1477592

Q9VIJ0
Glyoxylate reductase/hydroxypyruvate reductase

1

0

High-throughput

0.265

Low

1478168

Q9VJ53
GEO11831p1

1

0

High-throughput

0.265

Low

1478262

Q9VJ98
GH05617p

1

0

High-throughput

0.265

Low

1478412

Q9VJD8
AT13217p1

1

0

High-throughput

0.265

Low

1480987

Q9VLR0
FI06011p

1

0

High-throughput

0.265

Low

1481269

Q9VLU9
Uncharacterized protein, isoform E

1

0

High-throughput

0.265

Low

1481802

Q9VMJ2
RT07854p

1

0

High-throughput

0.265

Low

1483125

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.265

Low

1483243

Q9VPE6
LD43096p

1

0

High-throughput

0.265

Low

1484513

Q9VQY8
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.265

Low

1484728

PNO1
RNA-binding protein pno1

1

0

High-throughput

0.265

Low

1486173

Q9VTP5
RE41410p

1

0

High-throughput

0.265

Low

1486273

Q9VTV7
Uncharacterized protein

1

0

High-throughput

0.265

Low

1486587

AGT2L
Alanine--glyoxylate aminotransferase 2-like

1

0

High-throughput

0.265

Low

1486854

Q9VUL2
GH20023p

1

0

High-throughput

0.265

Low

1487058

Q9VV38
Phenoloxidase-activating factor 2

1

0

High-throughput

0.265

Low

1487247

Q9VVC2
Uncharacterized protein

1

0

High-throughput

0.265

Low

1487409

ATRIP
ATR-interacting protein mus304

1

0

High-throughput

0.265

Low

1487504

Q9VVW9
IP09370p

1

0

High-throughput

0.265

Low

1488150

Q9VX94
RE69682p

1

0

High-throughput

0.265

Low

1488451

Q9VXS3
LD21346p

1

0

High-throughput

0.265

Low

1488686

Q9VYD4
GEO12007p1

1

0

High-throughput

0.265

Low

1488771

MSHN
Moonshiner

1

0

High-throughput

0.265

Low

1488851

COMDA
COMM domain-containing protein 10 homolog Vlet

1

0

High-throughput

0.265

Low

1488971

Q9VZC0
Uncharacterized protein

1

0

High-throughput

0.265

Low

1489227

Q9W029
FI16876p1

1

0

High-throughput

0.265

Low

1489322

Q9W0F5
Uncharacterized protein

1

0

High-throughput

0.265

Low

1489568

Q9W1G1
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1489900

Q9W3S0
GH24548p

1

0

High-throughput

0.265

Low

1490056

Q9W4L6
GEO10192p1

1

0

High-throughput

0.265

Low

1490058

Q9W5C8
Uncharacterized protein

1

0

High-throughput

0.265

Low

84529

B7YZM8
Bardet-Biedl syndrome 9

1

0

High-throughput

0.251

Low

118334

M9NDC4
Uncharacterized protein, isoform G

1

0

High-throughput

0.251

Low

1237407

Q6NQZ3
LD16296p

1

0

High-throughput

0.238

Low

1484183

SNAPN
SNAPIN protein homolog

1

0

High-throughput

0.238

Low

1305218

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025