HitPredict

Interactor 1: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Interactor 2: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 16364915
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 582
+	Hs
		644289 TTP_HUMAN (1-326): 7.74e-64: 206: 100.00		DCP1B_HUMAN (4-575): 2.69e-53: 193: 27.96
+	Zm
		21714 A0A1D6MXR5_MAIZE (20-320): 1.33e-44: 162: 16.88		A0A1D6HWS4_MAIZE (6-352): 5.32e-52: 184: 19.72
+	Hs
		203252 UNK_HUMAN (71-300): 1.41e-30: 123: 16.12		SYNJ1_HUMAN (256-527): 1.61e-10: 66.3: 11.86