HitPredict

Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Interactor 2: KCNKI (Q7Z418)
Potassium channel subfamily K member 18 (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel)
Gene: KCNK18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 384
+	Hs
		738366 BMR1A_HUMAN (59-488): 2.92e-128: 385: 33.41		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		740000 TGFR2_HUMAN (28-493): 8.82e-123: 372: 33.79		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		738555 TGFR1_HUMAN (60-488): 5.17e-120: 363: 32.31		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		981124 ACVR1_HUMAN (47-493): 6.71e-117: 355: 30.27		KCNKI_HUMAN (1-384): 1.4e-131: 384: 100.00
+	Hs
		1044919 AVR2B_HUMAN (4-513): 2.64e-141: 418: 67.12		KCNT2_HUMAN (283-368): 2.85e-19: 91.8: 24.72