HitPredict

Interactor 1: HS901 (P27323)
Heat shock protein 90-1 (AtHSP90.1) (AtHsp90-1) (Heat shock protein 81-1) (Hsp81-1) (Heat shock protein 83)
Gene: HSP90-1

Interactor 2: SGT1B (Q9SUT5)
Protein SGT1 homolog B (AtSGT1b) (Protein ENHANCED DOWNY MILDEW 1) (Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 3) (Suppressor of G2 allele of SKP1 homolog B)
Gene: SGT1B

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.822

Property	Details
Experiments	18065690, 18032631
Identification Methods	two hybrid, pull down, x-ray crystallography
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 700 At			1 358
+	At
		646596 HS901_ARATH (1-700): 0: 1039: 100.00		SGT1A_ARATH (1-357): 1.94e-79: 248: 76.75
+	Hs
		438644 HS90B_HUMAN (6-700): 0: 1027: 68.77		SGT1_HUMAN (2-356): 5.21e-69: 222: 34.82
+	Hs
		438533 HS90B_HUMAN (6-700): 0: 1027: 68.77		RPAP3_HUMAN (2-267): 1.55e-43: 161: 18.45
+	At
		99226 HS901_ARATH (1-700): 0: 1039: 100.00		OE64M_ARATH (2-117): 8.91e-39: 147: 28.45
+	At
		646594 HS901_ARATH (1-700): 0: 1039: 100.00		OE64C_ARATH (2-115): 1.62e-36: 141: 31.58
+	Mm
		513680 HS90B_MOUSE (6-700): 0: 1028: 69.09		PPP5_MOUSE (2-241): 2.54e-36: 139: 21.67
+	Mm
		432427 HS90A_MOUSE (3-700): 0: 1026: 69.76		PPP5_MOUSE (2-241): 2.54e-36: 139: 21.67
+	Hs
		438021 HS90B_HUMAN (6-700): 0: 1027: 68.77		PPP5_HUMAN (2-241): 1.1e-35: 137: 21.25
+	Hs
		111935 K9JA46_HUMAN (3-700): 0: 1024: 69.86		PPP5_HUMAN (2-241): 1.1e-35: 137: 21.25
+	Hs
		431681 HS90A_HUMAN (3-700): 0: 1024: 69.86		PPP5_HUMAN (2-241): 1.1e-35: 137: 21.25
+	Hs
		174561 HS90B_HUMAN (6-700): 0: 1027: 68.77		OGT1_HUMAN (2-225): 4.65e-25: 108: 13.48
+	Hs
		174556 HS90A_HUMAN (3-700): 0: 1024: 69.86		OGT1_HUMAN (2-225): 4.65e-25: 108: 13.48
+	Hs
		437930 HS90B_HUMAN (6-700): 0: 1027: 68.77		STIP1_HUMAN (2-148): 2.73e-17: 84.8: 22.73
+	Hs
		111934 K9JA46_HUMAN (3-700): 0: 1024: 69.86		STIP1_HUMAN (2-148): 2.73e-17: 84.8: 22.73
+	Hs
		431574 HS90A_HUMAN (3-700): 0: 1024: 69.86		STIP1_HUMAN (2-148): 2.73e-17: 84.8: 22.73
+	Hs
		213454 HS90B_HUMAN (6-700): 0: 1027: 68.77		SGTA_HUMAN (43-165): 8.18e-11: 64.1: 18.70
+	Hs
		297025 HS90B_HUMAN (6-700): 0: 1027: 68.77		TOM70_HUMAN (6-327): 5.75e-10: 62.5: 11.32
+	Hs
		213451 HS90A_HUMAN (3-700): 0: 1024: 69.86		SGTA_HUMAN (43-165): 8.18e-11: 64.1: 18.70
+	Hs
		297024 HS90A_HUMAN (3-700): 0: 1024: 69.86		TOM70_HUMAN (6-327): 5.75e-10: 62.5: 11.32
+	Hs
		438464 HS90B_HUMAN (6-700): 0: 1027: 68.77		DNJC7_HUMAN (2-197): 5.41e-09: 59.5: 13.68