HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MPIP1 (P30304)
M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)
Gene: CDC25A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	28330616, 14559997, 15161933, 19289404
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, far western blotting, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 524
+	Hs
		673381 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP1_HUMAN (1-524): 0: 723: 100.00
+	Hs
		673382 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP1_HUMAN (1-524): 0: 723: 100.00
+	Hs
		673365 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP1_HUMAN (1-524): 0: 723: 100.00
+	Rn
		823139 1433E_RAT (2-243): 1.31e-144: 406: 63.53		MPIP1_RAT (1-524): 0: 673: 84.09
+	Hs
		673366 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP1_HUMAN (1-524): 0: 723: 100.00
+	Rn
		823141 1433E_RAT (2-243): 1.31e-144: 406: 63.53		MPIP2_RAT (30-522): 0: 564: 41.51
+	Hs
		673463 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP2_HUMAN (32-522): 0: 544: 43.02
+	Hs
		646656 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MPIP2_HUMAN (32-522): 0: 544: 43.02
+	Hs
		673464 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP2_HUMAN (32-522): 0: 544: 43.02
+	Hs
		673452 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP2_HUMAN (32-522): 0: 544: 43.02
+	Mm
		673543 1433B_MOUSE (1-242): 2.84e-124: 354: 80.99		MPIP2_MOUSE (30-522): 0: 565: 42.75
+	Xl
		223343 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		MPIP2_XENLA (34-524): 6.68e-172: 500: 37.24
+	Hs
		673560 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46
+	Hs
		673453 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP2_HUMAN (32-522): 0: 544: 43.02
+	Hs
		646657 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46
+	Hs
		673562 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46
+	Hs
		673545 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46
+	Rn
		89019 1433E_RAT (2-243): 1.31e-144: 406: 63.53		D4ADT2_RAT (31-523): 1.86e-140: 414: 30.42
+	Mm
		823143 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MPIP3_MOUSE (1-523): 2.66e-127: 380: 29.02
+	Hs
		673546 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46