HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ATX2L (Q8WWM7)
Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)
Gene: ATXN2L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1075
+	Hs
		909862 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		927346 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		683578 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		684237 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		982330 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		904919 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		909712 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		647025 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		927196 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		683472 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		927045 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MDC1_HUMAN (4-779): 4.69e-18: 92.3: 9.29
+	Ce
		89756 14332_CAEEL (3-241): 2.09e-116: 334: 77.41		D4PH96_CAEEL (120-821): 2.28e-34: 145: 14.48
+	Hs
		297821 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		K0754_HUMAN (3-350): 3.45e-09: 63.4: 12.00
+	Hs
		297824 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		K0754_HUMAN (3-350): 3.45e-09: 63.4: 12.00
+	Hs
		297815 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		K0754_HUMAN (3-350): 3.45e-09: 63.4: 12.00
+	Hs
		982175 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		904746 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		OTOG_HUMAN (598-1052): 3.47e-22: 106: 12.28
+	Hs
		203222 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		SYNJ1_HUMAN (668-1074): 8.77e-10: 65.4: 12.90
+	Hs
		203217 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		SYNJ1_HUMAN (668-1074): 8.77e-10: 65.4: 12.90