HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29509190, 11266503
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 530
+	Hs
		909878 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		927369 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		683595 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369315 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369023 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369354 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369070 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		684247 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		320172 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		369071 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		509305 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		369308 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		509343 1433B_MOUSE (1-242): 2.84e-124: 354: 80.99		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		377131 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377266 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		509296 1433G_MOUSE (1-242): 5.48e-105: 305: 70.33		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		487149 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487313 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		437636 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		487359 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59