HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ULK4 (Q96C45)
Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)
Gene: ULK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1275
+	Xl
		223344 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		Q804T2_XENLA (3-702): 3.26e-171: 527: 16.09
+	Mm
		910234 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK2_MOUSE (3-702): 2.83e-168: 521: 15.18
+	Hs
		647862 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK3_HUMAN (3-702): 2.19e-167: 518: 15.07
+	Mm
		910231 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK3_MOUSE (3-702): 1.13e-166: 516: 16.64
+	Xl
		223345 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		Q8QGV3_XENLA (3-702): 5.35e-162: 505: 15.08
+	Hs
		909730 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK2_HUMAN (3-702): 3.35e-156: 490: 14.75
+	Hs
		910106 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK1_HUMAN (3-702): 2.96e-155: 488: 14.67
+	Mm
		910318 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK1_MOUSE (3-702): 8.21e-153: 481: 14.67
+	Hs
		909524 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ROCK1_HUMAN (2-754): 1.16e-130: 436: 15.22
+	Hs
		909916 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK4_HUMAN (3-704): 1.38e-135: 434: 14.31
+	Mm
		910308 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK4_MOUSE (3-704): 9.21e-136: 434: 14.04
+	Hs
		229938 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NUAK1_HUMAN (3-635): 9.4e-128: 410: 15.28
+	Mm
		910266 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NUAK1_MOUSE (3-635): 8.71e-128: 410: 15.74
+	Hs
		681770 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKT1_HUMAN (1-349): 3.89e-122: 389: 21.33
+	Hs
		909692 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ULK3_HUMAN (1-279): 2.62e-32: 134: 32.88
+	Hs
		200101 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAPK3_HUMAN (2-283): 1.1e-26: 117: 30.07
+	Hs
		910114 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PAK5_HUMAN (1-283): 5.31e-26: 117: 32.17
+	Hs
		330944 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PAK4_HUMAN (1-283): 4.97e-25: 113: 29.37
+	Hs
		910063 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PAK6_HUMAN (7-279): 7e-25: 113: 29.35
+	Hs
		262252 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ULK1_HUMAN (10-247): 4.69e-24: 112: 28.63