Interactor 1: VATL (P27449)
V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c)
Gene: ATP6V0C

Interactor 2: VPP4 (Q9HBG4)
V-type proton ATPase 116 kDa subunit a 4 (V-ATPase 116 kDa isoform a 4) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform)
Gene: ATP6V0A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_C~V_ATPase_I
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
and 7 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 155
Hs

1 840
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024