HitPredict

Interactor 1: H2AX (P27661)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: HMGA2 (P52927)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26045162
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001673 - male germ cell nucleus GO:0005634 - nucleus GO:0007283 - spermatogenesis GO:0019899 - enzyme binding GO:0031492 - nucleosomal DNA binding and 1 others more... GO:0051321 - meiotic cell cycle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Mm			1 108
+	Hs
		555367 H2AX_HUMAN (1-143): 5.2e-74: 218: 97.20		HMGA2_HUMAN (1-108): 5.11e-41: 133: 95.41
+	Mm
		857682 H2A3_MOUSE (1-129): 5.66e-66: 198: 90.70		HMGA2_MOUSE (1-108): 1.28e-42: 136: 100.00
+	Hs
		857503 H2A1J_HUMAN (1-128): 9.7e-67: 199: 91.41		HMGA2_HUMAN (1-108): 5.11e-41: 133: 95.41
+	Hs
		857497 H2A1C_HUMAN (1-129): 4.5e-66: 198: 91.47		HMGA2_HUMAN (1-108): 5.11e-41: 133: 95.41
+	Mm
		857885 H2AY_MOUSE (1-142): 6.7e-62: 195: 60.69		HMGA2_MOUSE (1-108): 1.28e-42: 136: 100.00
+	Hs
		857476 H2A2C_HUMAN (1-129): 3.5e-65: 196: 89.92		HMGA2_HUMAN (1-108): 5.11e-41: 133: 95.41
+	Hs
		260809 H2AY_HUMAN (1-142): 1.05e-61: 195: 60.69		HMGA2_HUMAN (1-108): 5.11e-41: 133: 95.41