Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1
Interactor 2: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.90 | 0.935 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24126761, 9461578, 37827155, 26496610, 26474068, 27723720, 24981860, 11927569, 8663111, 28854355, 21504906, 19338310, 7760808, 8972858, 8663296, 10336450, 12509449 |
| Identification Methods | affinity chromatography technology, biochemical, proximity labelling technology, x-ray crystallography, two hybrid, cosedimentation in solution, coimmunoprecipitation, cosedimentation through density gradient, molecular sieving, tandem affinity purification and 2 others
more... |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rep_fac-A_3~Rep_fac-A_C, Rep_fac-A_3~tRNA_anti-codon |
| Common GO terms | GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0003684 - damaged DNA binding GO:0003697 - single-stranded DNA binding GO:0005654 - nucleoplasm and 7 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
