Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: RFA4 (Q13156)
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)
Gene: RPA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 25499885, 26186194, 28514442, 7760808, 33961781, 37827155
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, coimmunoprecipitation, cosedimentation in solution, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 616
Hs

1 261
+ Hs
+ At
+ Os
+ At
+ Dm
+ Sc
+ Ca
+ Ce
+ Os

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024