Protein: RFX1
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)

Gene: RFX1
Organism: Homo sapiens
Interactions: 74
UniProt ID: P22670

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

651093

FOXJ1
Forkhead box protein J1

4

20

High-throughput

0.697

High

651062

FOXN2
Forkhead box protein N2

3

20

High-throughput

0.678

High

133845

FOXN3
Forkhead box protein N3

3

20

High-throughput

0.662

High

651067

RFX3
Transcription factor RFX3

3

9

High-throughput

0.662

High

651077

HDAC1
Histone deacetylase 1

3

11

Small-scale

0.650

High

651109

HSPB8
Heat shock protein beta-8

2

3

High-throughput

0.628

High

651110

FBXL3
F-box/LRR-repeat protein 3

3

1

High-throughput

0.609

High

651061

ARRB2
Beta-arrestin-2

2

0

High-throughput

0.602

High

142833

NFIB
Nuclear factor 1 B-type

2

15

Small-scale

0.584

High

473786

NFIC
Nuclear factor 1 C-type

2

19

Small-scale

0.584

High

651080

NFIX
Nuclear factor 1 X-type

2

18

Small-scale

0.584

High

651100

INP5K
Inositol polyphosphate 5-phosphatase K

2

1

High-throughput

0.574

High

362161

ABL1
Tyrosine-protein kinase ABL1

1

17

Small-scale

0.561

High

651114

MAGD1
Melanoma-associated antigen D1

1

6

High-throughput

0.541

High

208180

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.536

High

290454

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

651065

NOTC1
Neurogenic locus notch homolog protein 1

1

3

High-throughput

0.536

High

651068

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.536

High

651079

FHL2
Four and a half LIM domains protein 2

1

7

High-throughput

0.536

High

651084

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.536

High

651104

E41L5
Band 4.1-like protein 5

1

6

High-throughput

0.536

High

651108

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

284797

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.518

High

181854

SMAD9
Mothers against decapentaplegic homolog 9

1

7

High-throughput

0.508

High

651076

SMAD4
Mothers against decapentaplegic homolog 4

1

8

High-throughput

0.508

High

651081

SMAD1
Mothers against decapentaplegic homolog 1

1

7

High-throughput

0.508

High

651064

ADDA
Alpha-adducin

1

3

Small-scale

0.506

High

346852

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

348850

CLIC3
Chloride intracellular channel protein 3

1

1

High-throughput

0.489

High

651059

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.489

High

651078

ARHG7
Rho guanine nucleotide exchange factor 7

1

1

High-throughput

0.489

High

651088

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

3

High-throughput

0.489

High

651089

F133A
Protein FAM133A

1

1

High-throughput

0.489

High

651096

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

2

High-throughput

0.489

High

651103

PAAT
ATPase PAAT

1

2

High-throughput

0.489

High

651105

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.489

High

128778

MEN1
Menin

1

2

High-throughput

0.479

High

190042

FOXP2
Forkhead box protein P2

1

20

Small-scale

0.479

High

403824

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

536506

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

587920

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

606227

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

651060

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

651063

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

651066

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

651069

CEBPA
CCAAT/enhancer-binding protein alpha

1

14

High-throughput

0.479

High

651071

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

651072

H33
Histone H3.3

1

11

High-throughput

0.479

High

651073

NFIA
Nuclear factor 1 A-type

1

18

High-throughput

0.479

High

651074

TP53B
TP53-binding protein 1

1

6

High-throughput

0.479

High

651075

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

651082

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

651086

FOXP4
Forkhead box protein P4

1

20

Small-scale

0.479

High

651087

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

651090

SP7
Transcription factor Sp7

1

11

High-throughput

0.479

High

651091

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

651097

CIC
Protein capicua homolog

1

19

High-throughput

0.479

High

651099

FEV
Protein FEV

1

15

High-throughput

0.479

High

651102

FOXP1
Forkhead box protein P1

1

20

Small-scale

0.479

High

651106

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

651107

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

651112

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

Small-scale

0.479

High

651113

KLF12
Krueppel-like factor 12

1

15

High-throughput

0.479

High

651115

NCOA3
Nuclear receptor coactivator 3

1

16

Small-scale

0.479

High

651092

RREB1
Ras-responsive element-binding protein 1

1

0

High-throughput

0.458

High

651095

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

651111

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

651094

IGSF8
Immunoglobulin superfamily member 8

1

4

High-throughput

0.445

High

651098

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

240761

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.437

High

651070

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.437

High

651085

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

651101

XYLT2
Xylosyltransferase 2

1

1

High-throughput

0.437

High

651083

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025