HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006310 - DNA recombination
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 471
+	Hs
		651110 RFA1_HUMAN (1-616): 0: 781: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		651802 RFA1_HUMAN (1-616): 0: 781: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516368 RFA1_HUMAN (1-616): 0: 781: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		613341 RFA1_HUMAN (1-616): 0: 781: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		651301 RFA1_HUMAN (1-616): 0: 781: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		651643 RFA1_HUMAN (1-616): 0: 781: 100.00		RAVR1_HUMAN (76-221): 8.34e-12: 69.4: 24.70
+	Hs
		652146 RFA1_HUMAN (1-616): 0: 781: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71