HitPredict

Interactor 1: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26496610, 27880917, 28330616, 36836934
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0010288 - response to lead ion
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 309
+	Hs
		653239 HEMH_HUMAN (1-423): 0: 599: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		653167 HEMH_HUMAN (1-423): 0: 599: 100.00		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Sc
		598308 HEMH_YEAST (63-417): 3.39e-154: 443: 50.14		PP2A1_YEAST (10-309): 0: 516: 76.00