HitPredict

Interactor 1: MAP4 (P27816)
Microtubule-associated protein 4 (MAP-4)
Gene: MAP4

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1152 Hs			1 2610
+	Hs
		497787 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		311839 TACC2_HUMAN (535-1151): 3.83e-11: 69.9: 9.50		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		125172 MAP4_HUMAN (1-1152): 1.33e-115: 388: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		503303 MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		497461 TAU_HUMAN (367-1125): 2.98e-44: 174: 21.01		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		503299 MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		503297 MTAP2_HUMAN (64-1125): 1.27e-31: 136: 15.31		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Hs
		1170093 SRCAP_HUMAN (448-1150): 2.04e-12: 74.4: 8.92		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		304168 MDC1_HUMAN (123-1019): 3.36e-19: 96.5: 11.77		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		554367 MUC1_HUMAN (292-1100): 3.81e-45: 180: 16.01		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		304267 TITIN_HUMAN (330-1131): 1.01e-11: 72.1: 11.93		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304244 MINK1_HUMAN (638-935): 1.29e-09: 65: 15.48		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1264807 TITIN_HUMAN (330-1131): 1.01e-11: 72.1: 11.93		SMUF2_HUMAN (2235-2607): 4.78e-118: 395: 20.62
+	Hs
		1233533 MINK1_HUMAN (638-935): 1.29e-09: 65: 15.48		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Mm
		103609 MICA3_MOUSE (552-990): 7.65e-28: 124: 14.73		ANK3_MOUSE (8-1037): 1.34e-90: 331: 12.59
+	Dm
		65570 FUTSC_DROME (15-1123): 5.75e-23: 109: 10.75		A8JNM5_DROME (44-853): 2.71e-89: 329: 12.15
+	Hs
		1056563 MDC1_HUMAN (123-1019): 3.36e-19: 96.5: 11.77		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		556716 TITIN_HUMAN (330-1131): 1.01e-11: 72.1: 11.93		ANK1_HUMAN (354-913): 1.43e-61: 237: 12.27
+	Dm
		1182373 Q9VLS7_DROME (513-1146): 2.05e-10: 67.6: 8.20		Q7KU92_DROME (356-967): 3.45e-61: 236: 12.04