HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	32707033, 35384245, 36736316
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 894
+	Hs
		654090 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA3_HUMAN (2-831): 0: 646: 19.34
+	Hs
		654091 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA8_HUMAN (2-824): 0: 590: 19.20
+	Hs
		654413 CALX_HUMAN (1-592): 0: 786: 100.00		EPHAA_HUMAN (2-837): 2.59e-158: 491: 18.61
+	Hs
		411305 CALX_HUMAN (1-592): 0: 786: 100.00		INSR_HUMAN (272-851): 1.65e-136: 443: 27.97
+	Hs
		653493 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		160999 CLGN_HUMAN (11-546): 0: 652: 59.85		INSR_HUMAN (272-851): 1.65e-136: 443: 27.97
+	Hs
		441438 CALX_HUMAN (1-592): 0: 786: 100.00		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		653574 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		MERTK_HUMAN (7-861): 0: 588: 40.53
+	Hs
		445825 CALX_HUMAN (1-592): 0: 786: 100.00		ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27
+	Hs
		601462 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46
+	Hs
		653619 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		EPHAA_HUMAN (2-837): 2.59e-158: 491: 18.61
+	Hs
		161004 CLGN_HUMAN (11-546): 0: 652: 59.85		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Rn
		544766 CALR_RAT (67-470): 7.8e-147: 431: 37.35		INSR_RAT (276-851): 1.26e-134: 437: 27.83
+	Hs
		654279 CALX_HUMAN (1-592): 0: 786: 100.00		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		507869 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435545 CALX_HUMAN (1-592): 0: 786: 100.00		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		161056 CLGN_HUMAN (11-546): 0: 652: 59.85		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		161008 CLGN_HUMAN (11-546): 0: 652: 59.85		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		161003 CLGN_HUMAN (11-546): 0: 652: 59.85		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		441437 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		MET_HUMAN (536-799): 3.42e-66: 243: 45.90