HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27880917, 27432908
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 979
+	Hs
		653610 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		PTPRN_HUMAN (29-979): 0: 753: 100.00
+	Hs
		573579 CALX_HUMAN (1-592): 0: 786: 100.00		PTN1_HUMAN (698-974): 4.8e-118: 370: 35.76
+	Hs
		576987 CALX_HUMAN (1-592): 0: 786: 100.00		PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77
+	Hs
		617040 CALX_HUMAN (1-592): 0: 786: 100.00		PTPRE_HUMAN (677-970): 6.27e-100: 330: 32.11
+	Mm
		724485 CALX_MOUSE (1-592): 0: 732: 90.56		PTN1_MOUSE (698-974): 2.01e-117: 368: 35.76
+	Hs
		654088 CALX_HUMAN (1-592): 0: 786: 100.00		PTPRM_HUMAN (678-973): 7.59e-61: 228: 28.95
+	Hs
		654626 CALX_HUMAN (1-592): 0: 786: 100.00		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		161128 CLGN_HUMAN (11-546): 0: 652: 59.85		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		573862 CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59		PTN1_HUMAN (698-974): 4.8e-118: 370: 35.76
+	Hs
		653680 CALR_HUMAN (67-470): 1.19e-141: 418: 38.33		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71