HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: NISCH (Q9Y2I1)
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)
Gene: NISCH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	27173435, 32203420, 35271311, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 1504
+	Hs
		129353 P85B_HUMAN (4-719): 6.38e-162: 486: 57.24		NISCH_HUMAN (1-1504): 0: 1812: 100.00
+	Hs
		1267457 P55G_HUMAN (271-723): 1.4e-104: 329: 72.31		NISCH_HUMAN (1-1504): 0: 1812: 100.00
+	Hs
		1133678 RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46		CNTRL_HUMAN (304-478): 2.54e-36: 153: 28.89