HitPredict

Interactor 1: A8JNP7 (A8JNP7)
Inhibitor-2, isoform B
Gene: I-2

Interactor 2: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.80	0.741

Property	Details
Experiments	14605208, 17007873, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Dm			1 302
+	Dm
		65575 A8JNP7_DROME (1-310): 2.33e-138: 395: 100.00		PP11_DROME (1-301): 0: 547: 96.68
+	Dm
		65577 A8JNP7_DROME (1-310): 2.33e-138: 395: 100.00		PP13_DROME (1-302): 0: 539: 93.71
+	Dm
		65576 A8JNP7_DROME (1-310): 2.33e-138: 395: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Mm
		906370 IPP2_MOUSE (106-289): 1.27e-66: 209: 35.12		PP1A_MOUSE (2-301): 0: 550: 92.33
+	Hs
		737628 IPP2_HUMAN (106-289): 1.38e-64: 203: 33.82		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		782714 IPP2_HUMAN (106-289): 1.38e-64: 203: 33.82		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		737869 IPP2B_HUMAN (106-289): 4.53e-63: 200: 33.33		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		905971 IPP2B_HUMAN (106-289): 4.53e-63: 200: 33.33		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Dm
		524639 Q9V3C7_DROME (106-310): 3.46e-61: 195: 100.00		PP12_DROME (1-302): 0: 547: 100.00
+	Dm
		819222 Q9V3C7_DROME (106-310): 3.46e-61: 195: 100.00		PP11_DROME (1-301): 0: 547: 96.68
+	Hs
		782715 IPP2_HUMAN (106-289): 1.38e-64: 203: 33.82		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Hs
		906500 IPP2B_HUMAN (106-289): 4.53e-63: 200: 33.33		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Dm
		524615 Q4V424_DROME (135-310): 1.21e-57: 188: 21.93		PP12_DROME (1-302): 0: 547: 100.00
+	Dm
		984191 Q9V3C7_DROME (106-310): 3.46e-61: 195: 100.00		PP13_DROME (1-302): 0: 539: 93.71
+	Hs
		164067 IPP2C_HUMAN (106-287): 2.51e-56: 182: 26.63		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		164068 IPP2C_HUMAN (106-287): 2.51e-56: 182: 26.63		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Dm
		819290 Q9V3C7_DROME (106-310): 3.46e-61: 195: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Hs
		164069 IPP2C_HUMAN (106-287): 2.51e-56: 182: 26.63		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Dm
		819260 Q4V424_DROME (135-310): 1.21e-57: 188: 21.93		PP1B_DROME (1-302): 0: 530: 85.48
+	Dm
		1118462 Q4V424_DROME (135-310): 1.21e-57: 188: 21.93		Q8T0U6_DROME (17-302): 0: 516: 87.06