HitPredict

Interactor 1: BRAF (P28028)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)
Gene: BRAF

Interactor 2: COPA (Q8CIE6)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 751 Mm			1 1224
+	Hs
		542841 BRAF_HUMAN (31-751): 0: 676: 90.90		COPA_HUMAN (1-1224): 0: 1322: 98.45
+	Hs
		373927 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		COPA_HUMAN (1-1224): 0: 1322: 98.45
+	Hs
		488631 ARAF_HUMAN (124-735): 6.32e-164: 488: 56.17		COPA_HUMAN (1-1224): 0: 1322: 98.45
+	Hs
		384549 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		COPA_HUMAN (1-1224): 0: 1322: 98.45
+	Hs
		375094 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		WDR3_HUMAN (327-517): 2.58e-21: 102: 11.06
+	Zm
		38002 A0A1D6PVN4_MAIZE (254-700): 7.21e-134: 412: 20.81		A0A1D6MEH7_MAIZE (83-514): 8.86e-50: 186: 18.63
+	Hs
		384386 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		COPB2_HUMAN (196-996): 2.78e-49: 192: 12.32
+	Hs
		373991 RAF1_HUMAN (126-740): 1.21e-172: 512: 56.15		WDR5_HUMAN (520-631): 1.39e-10: 66.2: 11.21
+	Hs
		384438 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		LIS1_HUMAN (198-526): 3.31e-34: 138: 16.96
+	Hs
		384596 NTRK1_HUMAN (106-707): 2.27e-127: 400: 18.57		WDR5_HUMAN (520-631): 1.39e-10: 66.2: 11.21
+	Zm
		38001 A0A1D6NRI5_MAIZE (392-727): 4.17e-39: 158: 31.32		A0A1D6MEH7_MAIZE (83-514): 8.86e-50: 186: 18.63