HitPredict

Interactor 1: PSB8 (P28062)
Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)
Gene: PSMB8

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 276 Hs			1 154
+	Hs
		771484 PSB10_HUMAN (37-261): 8.91e-75: 231: 27.07		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1198660 PSB7_HUMAN (70-264): 7.13e-84: 254: 26.15		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		656744 PSB5_HUMAN (1-272): 5.65e-83: 251: 58.09		RN149_HUMAN (54-147): 1.09e-25: 102: 34.04
+	Hs
		656740 PSB5_HUMAN (1-272): 5.65e-83: 251: 58.09		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		656739 PSB5_HUMAN (1-272): 5.65e-83: 251: 58.09		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		656265 PSA5_HUMAN (49-271): 1.86e-82: 249: 16.81		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		656627 PSB6_HUMAN (52-255): 8.9e-80: 242: 31.22		RN149_HUMAN (54-147): 1.09e-25: 102: 34.04
+	Hs
		637715 PSA2_HUMAN (49-272): 1.11e-79: 242: 19.31		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		638163 PSA4_HUMAN (47-268): 1.58e-79: 242: 16.88		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		656623 PSB6_HUMAN (52-255): 8.9e-80: 242: 31.22		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		893707 PSA6_HUMAN (43-275): 8.03e-80: 242: 13.31		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		637713 PSA2_HUMAN (49-272): 1.11e-79: 242: 19.31		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		656622 PSB6_HUMAN (52-255): 8.9e-80: 242: 31.22		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40
+	Hs
		893702 PSA6_HUMAN (43-275): 8.03e-80: 242: 13.31		SYVN1_HUMAN (72-152): 3.43e-24: 99.2: 28.40