HitPredict

Interactor 1: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35358511, 27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Hs			1 399
+	Hs
		656249 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		1136648 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		656750 PSB5_HUMAN (1-263): 2.38e-93: 277: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		656280 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		1259549 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		656793 PSB5_HUMAN (1-263): 2.38e-93: 277: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		656789 PSB5_HUMAN (1-263): 2.38e-93: 277: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656783 PSB5_HUMAN (1-263): 2.38e-93: 277: 100.00		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		656337 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		656327 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1303496 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		1303490 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		656323 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Dm
		1178971 Q7K148_DROME (1-260): 9.47e-85: 256: 51.46		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Dm
		1374384 Q9VUJ1_DROME (62-253): 1.16e-84: 255: 27.08		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Dm
		1278653 PSA5_DROME (28-259): 3.23e-84: 253: 16.67		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		656689 PSB5_HUMAN (1-263): 2.38e-93: 277: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		656183 PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Sc
		689162 PSA5_YEAST (28-260): 1.87e-80: 244: 17.89		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Hs
		924123 PSB7_HUMAN (39-251): 2.76e-83: 252: 25.82		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06