Interactor 1: 5HT2A (P28223)
5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)
Gene: HTR2A

Interactor 2: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26158621
Identification Methods bioluminescence resonance energy transfer
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms GO:0005886 - plasma membrane
GO:0031410 - cytoplasmic vesicle
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
GO:0098978 - glutamatergic synapse
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 471
Hs

1 409
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024