Interactor 1: 5HT2A (P28223)
5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)
Gene: HTR2A

Interactor 2: GRM2 (Q14416)
Metabotropic glutamate receptor 2 (mGluR2)
Gene: GRM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.589

The method score is based on:

Property Details
Experiments 18297054
Identification Methods anti tag coimmunoprecipitation, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, bioluminescence resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0014059 - regulation of dopamine secretion
GO:0030424 - axon
GO:0030425 - dendrite
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 471
Hs

1 872
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024