Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.774

The method score is based on:

Property Details
Experiments 15616583
Identification Methods two hybrid, pull down, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Pkinase, Ank_2~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 360
Hs

1 1430
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024