Interactor 1: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.608

The method score is based on:

Property Details
Experiments 26267535
Identification Methods affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 360
Hs

1 327
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024