HitPredict

Interactor 1: KCC2B (P28652)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: Camk2b

Interactor 2: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0043005 - neuron projection and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 542 Mm			1 677
+	Hs
		843655 KCC2G_HUMAN (1-542): 0: 579: 77.14		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Mm
		515232 KCC2A_MOUSE (3-538): 6.08e-166: 481: 64.55		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Hs
		843969 KCC2A_HUMAN (3-538): 5.82e-166: 481: 64.55		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		844046 KCC2G_HUMAN (1-542): 0: 579: 77.14		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Hs
		844047 KCC2D_HUMAN (1-542): 1.44e-173: 501: 65.87		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Mm
		659466 KCC2B_MOUSE (1-542): 0: 635: 100.00		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		1207083 KCC2G_MOUSE (1-542): 0: 596: 81.25		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Hs
		843654 KCC2B_HUMAN (279-542): 3.56e-46: 173: 53.03		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Mm
		1161535 KCC2D_MOUSE (1-542): 1.44e-173: 501: 65.87		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		515247 KCC2A_MOUSE (3-538): 6.08e-166: 481: 64.55		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Hs
		844045 KCC2B_HUMAN (279-542): 3.56e-46: 173: 53.03		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Mm
		659445 KCC2B_MOUSE (1-542): 0: 635: 100.00		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		729581 KCC2G_MOUSE (1-542): 0: 596: 81.25		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		729519 KCC2D_MOUSE (1-542): 1.44e-173: 501: 65.87		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		515218 KCC2A_MOUSE (3-538): 6.08e-166: 481: 64.55		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Hs
		989201 KCC2A_HUMAN (3-538): 5.82e-166: 481: 64.55		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Hs
		159196 CSKP_HUMAN (10-308): 5.16e-84: 281: 46.73		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Hs
		988863 KCC2B_HUMAN (279-542): 3.56e-46: 173: 53.03		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10