HitPredict

Interactor 1: ERCC5 (P28715)
DNA excision repair protein ERCC-5 (EC 3.1.-.-) (DNA repair protein complementing XP-G cells) (XPG) (Xeroderma pigmentosum group G-complementing protein)
Gene: ERCC5

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1186 Hs			1 499
+	Hs
		833895 Q59FZ7_HUMAN (30-1170): 0: 1227: 99.65		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833746 Q59FZ7_HUMAN (30-1170): 0: 1227: 99.65		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		659908 ERCC5_HUMAN (1-1170): 0: 1220: 100.00		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834059 Q59FZ7_HUMAN (30-1170): 0: 1227: 99.65		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		1123951 Q59FZ7_HUMAN (30-1170): 0: 1227: 99.65		CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05
+	Hs
		659910 ERCC5_HUMAN (1-1170): 0: 1220: 100.00		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		659925 ERCC5_HUMAN (1-1170): 0: 1220: 100.00		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		625189 FEN1_HUMAN (1-377): 5.91e-54: 195: 17.75		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		414797 FEN1_HUMAN (1-377): 5.91e-54: 195: 17.75		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		625644 EXO1_HUMAN (1-702): 4.97e-14: 78.9: 12.69		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		415109 EXO1_HUMAN (1-702): 4.97e-14: 78.9: 12.69		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95