Interactor 1: CXB2 (P29033)
Gap junction beta-2 protein (Connexin-26) (Cx26)
Gene: GJB2

Interactor 2: CXA5 (P36382)
Gap junction alpha-5 protein (Connexin-40) (Cx40)
Gene: GJA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Connexin~Connexin
Common GO terms GO:0005886 - plasma membrane
GO:0005921 - gap junction
GO:0005922 - connexin complex
GO:0007267 - cell-cell signaling
GO:0016264 - gap junction assembly
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 226
Hs

1 358
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024