HitPredict

Interactor 1: TAU (P29172)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: 1433Z (P63103)
14-3-3 protein zeta/delta (Factor activating exoenzyme S) (FAS) (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12551948, 10840038
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Bt			1 245
+	Mm
		497995 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Mm
		497973 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Rn
		94197 F1LST4_RAT (10-447): 5.91e-62: 216: 67.56		1433Z_RAT (1-245): 3.48e-145: 407: 99.59
+	Rn
		581974 TAU_RAT (10-448): 6.81e-62: 215: 67.41		1433Z_RAT (1-245): 3.48e-145: 407: 99.59
+	Rn
		94188 F1LST4_RAT (10-447): 5.91e-62: 216: 67.56		1433E_RAT (2-241): 9.9e-144: 403: 68.18
+	Rn
		581965 TAU_RAT (10-448): 6.81e-62: 215: 67.41		1433E_RAT (2-241): 9.9e-144: 403: 68.18
+	Hs
		496795 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		496737 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Rn
		94200 F1LST4_RAT (10-447): 5.91e-62: 216: 67.56		1433T_RAT (1-245): 8.98e-140: 393: 79.18
+	Rn
		581977 TAU_RAT (10-448): 6.81e-62: 215: 67.41		1433T_RAT (1-245): 8.98e-140: 393: 79.18
+	Hs
		496356 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		496415 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Mm
		498123 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433B_MOUSE (1-242): 3.77e-128: 364: 87.19
+	Mm
		497971 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433G_MOUSE (1-240): 2.37e-108: 314: 74.59
+	Mm
		498003 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433F_MOUSE (2-240): 1.16e-107: 312: 74.07
+	Rn
		94187 F1LST4_RAT (10-447): 5.91e-62: 216: 67.56		1433G_RAT (1-240): 2.37e-108: 314: 74.59
+	Rn
		581964 TAU_RAT (10-448): 6.81e-62: 215: 67.41		1433G_RAT (1-240): 2.37e-108: 314: 74.59
+	Mm
		250865 TAU_MOUSE (10-448): 2.26e-65: 225: 68.16		1433S_MOUSE (1-232): 7.92e-104: 302: 73.08
+	Hs
		496727 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		496416 TAU_HUMAN (5-448): 6.96e-60: 210: 65.78		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97