Interactor 1: PTN6 (P29351)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (70Z-SHP) (Hematopoietic cell protein-tyrosine phosphatase) (PTPTY-42) (Protein-tyrosine phosphatase 1C) (PTP-1C) (SH-PTP1) (SHP-1)
Gene: Ptpn6

Interactor 2: LCP2 (Q60787)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 15668918
Identification Methods phosphatase assay, anti tag coimmunoprecipitation
Interaction Type dephosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~Y_phosphatase
Common GO terms GO:0005829 - cytosol
GO:0005911 - cell-cell junction
GO:0035556 - intracellular signal transduction
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 595
Mm

1 533
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024