Protein: IBP5
Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)

Gene: IBP5, IGFBP5
Organism: Homo sapiens
Interactions: 127
UniProt ID: P24593

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001649 - osteoblast differentiation
GO:0001968 - fibronectin binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377820

IGF2
Insulin-like growth factor 2

3

10

Small-scale

0.847

High

420275

IGF1
Insulin-like growth factor 1

2

10

Small-scale

0.778

High

665994

AMGO1
Amphoterin-induced protein 1

2

0

High-throughput

0.655

High

665952

ALS
Insulin-like growth factor-binding protein complex acid labile subunit

1

1

Small-scale

0.647

High

230262

CREB3
Cyclic AMP-responsive element-binding protein 3

2

2

High-throughput

0.628

High

188816

TMPS2
Transmembrane protease serine 2

2

6

High-throughput

0.606

High

213678

AQP9
Aquaporin-9

2

3

High-throughput

0.606

High

455901

ASGR1
Asialoglycoprotein receptor 1

2

1

High-throughput

0.606

High

622028

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.606

High

666007

GPX8
Probable glutathione peroxidase 8

2

2

High-throughput

0.606

High

665949

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.601

High

665980

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

665985

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.580

High

665995

AHNK2
Protein AHNAK2

2

0

High-throughput

0.580

High

666000

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.580

High

666022

S38A1
Sodium-coupled neutral amino acid symporter 1

2

0

High-throughput

0.580

High

665974

FHL2
Four and a half LIM domains protein 2

1

1

Small-scale

0.573

High

395509

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

258631

G37L1
G-protein coupled receptor 37-like 1

2

1

High-throughput

0.553

High

291723

CXB3
Gap junction beta-3 protein

2

3

High-throughput

0.553

High

335228

CXB5
Gap junction beta-5 protein

2

3

High-throughput

0.553

High

337863

CLD7
Claudin-7

2

5

High-throughput

0.553

High

338249

CLD9
Claudin-9

2

5

High-throughput

0.553

High

349621

TSN12
Tetraspanin-12

2

1

High-throughput

0.553

High

665948

CXCR1
C-X-C chemokine receptor type 1

2

3

High-throughput

0.553

High

665953

CXA5
Gap junction alpha-5 protein

2

3

High-throughput

0.553

High

665955

AQP2
Aquaporin-2

2

2

High-throughput

0.553

High

665958

CXA8
Gap junction alpha-8 protein

2

3

High-throughput

0.553

High

665960

CLD6
Claudin-6

2

5

High-throughput

0.553

High

665961

CLD20
Claudin-20

2

5

High-throughput

0.553

High

665962

CLD2
Claudin-2

2

5

High-throughput

0.553

High

665971

AQP6
Aquaporin-6

2

2

High-throughput

0.553

High

665981

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

7

High-throughput

0.553

High

665984

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

2

1

High-throughput

0.553

High

665987

LAYN
Layilin

2

3

High-throughput

0.553

High

665988

CL17A
C-type lectin domain family 17, member A

2

2

High-throughput

0.553

High

666001

PKR2
Prokineticin receptor 2

2

1

High-throughput

0.553

High

666005

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.553

High

666006

GP151
G-protein coupled receptor 151

2

2

High-throughput

0.553

High

666011

T106A
Transmembrane protein 106A

2

1

High-throughput

0.553

High

666013

S41A3
Solute carrier family 41 member 3

2

1

High-throughput

0.553

High

666014

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

1

High-throughput

0.553

High

666015

S41A2
Solute carrier family 41 member 2

2

1

High-throughput

0.553

High

666017

FCRL3
Fc receptor-like protein 3

2

2

High-throughput

0.553

High

666019

T106C
Transmembrane protein 106C

2

1

High-throughput

0.553

High

666020

MS4A7
Membrane-spanning 4-domains subfamily A member 7

2

1

High-throughput

0.553

High

666023

CHODL
Chondrolectin

2

3

High-throughput

0.553

High

665956

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.541

High

665973

FHL1
Four and a half LIM domains protein 1

1

1

High-throughput

0.541

High

374408

RASH
GTPase HRas

1

2

High-throughput

0.536

High

375185

RASK
GTPase KRas

1

2

High-throughput

0.536

High

451601

GPX1
Glutathione peroxidase 1

1

2

High-throughput

0.536

High

665950

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.536

High

665963

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.536

High

665965

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

High-throughput

0.536

High

665976

PDIA6
Protein disulfide-isomerase A6

1

3

High-throughput

0.515

High

294969

RPP40
Ribonuclease P protein subunit p40

1

0

High-throughput

0.513

High

332282

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.513

High

665967

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

0

High-throughput

0.513

High

209876

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

3

Small-scale

0.501

High

399546

VTNC
Vitronectin

1

2

Small-scale

0.501

High

464419

TSP1
Thrombospondin-1

1

8

Small-scale

0.501

High

665975

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

18

Small-scale

0.501

High

665957

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

1

High-throughput

0.489

High

665964

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

3

High-throughput

0.489

High

665983

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

3

High-throughput

0.489

High

666002

NBEA
Neurobeachin

1

1

High-throughput

0.489

High

666033

KLHL8
Kelch-like protein 8

1

3

High-throughput

0.489

High

194674

FFAR2
Free fatty acid receptor 2

1

5

High-throughput

0.481

High

522241

OSTP
Osteopontin

1

0

Small-scale

0.480

High

468085

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.479

High

540810

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.479

High

550847

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

665951

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

15

Small-scale

0.479

High

665972

CUL3
Cullin-3

1

3

High-throughput

0.479

High

193394

GPR42
G-protein coupled receptor 42

1

5

High-throughput

0.470

High

385467

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

666040

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.460

High

369835

CO3
Complement C3

1

0

High-throughput

0.458

High

424582

PAI1
Plasminogen activator inhibitor 1

1

0

Small-scale

0.458

High

665959

MASP1
Mannan-binding lectin serine protease 1

1

3

Small-scale

0.445

High

665996

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

2

Small-scale

0.445

High

666029

PNO1
RNA-binding protein PNO1

1

0

High-throughput

0.438

High

379726

IGHA2
Immunoglobulin heavy constant alpha 2

1

0

High-throughput

0.426

High

665966

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.407

High

666037

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

3

High-throughput

0.407

High

332782

KCNK5
Potassium channel subfamily K member 5

2

0

High-throughput

0.316

High

665969

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

665977

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

665979

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

665982

TSPO2
Translocator protein 2

2

0

High-throughput

0.316

High

665986

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.316

High

665989

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.316

High

665991

T179B
Transmembrane protein 179B

2

0

High-throughput

0.316

High

665992

LAP4B
Lysosomal-associated transmembrane protein 4B

2

0

High-throughput

0.316

High

665993

LHPL1
LHFPL tetraspan subfamily member 1 protein

2

0

High-throughput

0.316

High

665997

K2013
Uncharacterized protein KIAA2013

2

0

High-throughput

0.316

High

665998

SYNE4
Nesprin-4

2

0

High-throughput

0.316

High

666003

ABHD4
(Lyso)-N-acylphosphatidylethanolamine lipase

2

0

High-throughput

0.316

High

666004

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

666009

THAP4
Peroxynitrite isomerase THAP4

2

0

High-throughput

0.316

High

666010

BSND
Barttin

2

0

High-throughput

0.316

High

666012

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.316

High

666016

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.316

High

666018

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

666021

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

666024

CERS4
Ceramide synthase 4

2

0

High-throughput

0.316

High

666025

SPAG4
Sperm-associated antigen 4 protein

2

0

High-throughput

0.316

High

666030

TM45A
Transmembrane protein 45A

2

0

High-throughput

0.316

High

666031

ELOV5
Very long chain fatty acid elongase 5

2

0

High-throughput

0.316

High

666032

GPC5D
G-protein coupled receptor family C group 5 member D

2

0

High-throughput

0.316

High

666034

RHCG
Ammonium transporter Rh type C

2

0

High-throughput

0.316

High

666035

S13A4
Solute carrier family 13 member 4

2

0

High-throughput

0.316

High

666036

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

666038

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

666039

RT18B
Small ribosomal subunit protein mS40

2

0

High-throughput

0.316

High

325424

RPP14
Ribonuclease P protein subunit p14

1

0

High-throughput

0.279

Low

665954

TPOR
Thrombopoietin receptor

1

0

High-throughput

0.279

Low

665968

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.279

Low

665999

FXL16
F-box/LRR-repeat protein 16

1

0

High-throughput

0.279

Low

666008

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.279

Low

665970

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.251

Low

665978

AR13B
ADP-ribosylation factor-like protein 13B

1

0

High-throughput

0.251

Low

665990

CPLX4
Complexin-4

1

0

High-throughput

0.251

Low

666026

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.251

Low

666027

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.251

Low

666028

SAR1A
Small COPII coat GTPase SAR1A

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025