Protein: ASGR1
Asialoglycoprotein receptor 1 (ASGP-R 1) (ASGPR 1) (C-type lectin domain family 4 member H1) (Hepatic lectin H1) (HL-1)

Gene: ASGR1
Organism: Homo sapiens
Interactions: 57
UniProt ID: P07306

Gene Ontology (top 5):
GO:0004873 - asialoglycoprotein receptor activity
GO:0005537 - D-mannose binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

455936

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.742

High

455920

AMGO1
Amphoterin-induced protein 1

2

19

High-throughput

0.700

High

455914

CLC4G
C-type lectin domain family 4 member G

1

15

High-throughput

0.656

High

455900

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

11

High-throughput

0.628

High

337856

CLD7
Claudin-7

2

5

High-throughput

0.606

High

359902

NB5R3
NADH-cytochrome b5 reductase 3

2

1

High-throughput

0.606

High

455898

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

9

High-throughput

0.606

High

455901

IBP5
Insulin-like growth factor-binding protein 5

2

1

High-throughput

0.606

High

455905

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.606

High

455917

CPLX4
Complexin-4

2

1

High-throughput

0.606

High

455922

MCEM1
Mast cell-expressed membrane protein 1

2

1

High-throughput

0.606

High

455932

SUSD3
Sushi domain-containing protein 3

2

1

High-throughput

0.606

High

455943

AT1B4
Protein ATP1B4

2

1

High-throughput

0.606

High

455909

GABT
4-aminobutyrate aminotransferase, mitochondrial

2

0

High-throughput

0.602

High

455911

NTCP
Hepatic sodium/bile acid cotransporter

2

0

High-throughput

0.580

High

455921

AHNK2
Protein AHNAK2

2

0

High-throughput

0.580

High

455930

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.580

High

455931

CERS2
Ceramide synthase 2

2

2

Small-scale

0.565

High

455913

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

455915

RN19B
E3 ubiquitin-protein ligase RNF19B

2

2

High-throughput

0.553

High

455925

FNDC9
Fibronectin type III domain-containing protein 9

2

1

High-throughput

0.553

High

455926

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

455929

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

5

High-throughput

0.553

High

455937

SPAG4
Sperm-associated antigen 4 protein

2

5

High-throughput

0.553

High

455939

SAR1A
Small COPII coat GTPase SAR1A

2

6

High-throughput

0.553

High

455944

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

1

High-throughput

0.553

High

455918

GALT5
Polypeptide N-acetylgalactosaminyltransferase 5

1

8

High-throughput

0.536

High

455923

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

8

High-throughput

0.536

High

455924

GOLM1
Golgi membrane protein 1

1

2

High-throughput

0.536

High

421312

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

455904

SYUA
Alpha-synuclein

1

4

High-throughput

0.481

High

400132

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

455897

BIP
Endoplasmic reticulum chaperone BiP

1

8

Small-scale

0.479

High

455916

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

High-throughput

0.464

High

455906

GPC3
Glypican-3

1

6

High-throughput

0.445

High

455907

CD81
CD81 antigen

1

7

High-throughput

0.445

High

385370

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.439

High

455933

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

1

Small-scale

0.439

High

455902

CALX
Calnexin

1

15

Small-scale

0.437

High

455912

EEA1
Early endosome antigen 1

1

5

High-throughput

0.437

High

455919

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

5

Small-scale

0.437

High

455927

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

4

Small-scale

0.437

High

455940

FBX6
F-box only protein 6

1

6

Small-scale

0.437

High

455942

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

455934

PLVAP
Plasmalemma vesicle-associated protein

2

0

High-throughput

0.328

High

71836

LEUTX
Paired-like homeodomain transcription factor LEUTX

2

0

High-throughput

0.316

High

155541

NEMP1
Nuclear envelope integral membrane protein 1

2

0

High-throughput

0.316

High

455903

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.316

High

455908

BLCAP
Apoptosis inducing factor BLCAP

2

0

High-throughput

0.316

High

455910

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

455938

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

455945

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

455935

SPY4
Protein sprouty homolog 4

1

0

High-throughput

0.279

Low

455941

NLK
Serine/threonine-protein kinase NLK

1

0

High-throughput

0.265

Low

219121

LTOR5
Ragulator complex protein LAMTOR5

1

0

Small-scale

0.251

Low

455899

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.251

Low

455928

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025