HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: K1C9 (P35527)
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)
Gene: KRT9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 623
+	Hs
		531449 SHC1_HUMAN (1-583): 0: 531: 100.00		K1C13_HUMAN (141-478): 7.77e-151: 444: 53.25
+	Hs
		359306 SHC1_HUMAN (1-583): 0: 531: 100.00		K1C14_HUMAN (151-484): 1.87e-149: 441: 55.39
+	Hs
		445008 SHC1_HUMAN (1-583): 0: 531: 100.00		K1C16_HUMAN (149-478): 7.63e-142: 422: 54.85
+	Hs
		666076 SHC1_HUMAN (1-583): 0: 531: 100.00		K1C17_HUMAN (84-476): 1.12e-139: 415: 49.36
+	Hs
		280673 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90
+	Hs
		1149262 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		K1C40_HUMAN (80-486): 1.13e-139: 415: 35.12
+	Hs
		531536 SHC1_HUMAN (1-583): 0: 531: 100.00		K2C5_HUMAN (1-468): 2.71e-75: 253: 22.31
+	Hs
		359467 SHC1_HUMAN (1-583): 0: 531: 100.00		K2C6A_HUMAN (2-484): 5e-73: 246: 23.12
+	Hs
		1055072 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		KT33B_HUMAN (112-494): 5.12e-101: 314: 37.50
+	Hs
		213975 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		KRT86_HUMAN (37-509): 4.75e-86: 278: 20.89
+	Hs
		1071309 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		K1H1_HUMAN (105-479): 5.22e-77: 252: 37.60
+	Hs
		280597 Q49AR9_HUMAN (40-425): 1.96e-47: 176: 18.14		KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90
+	Hs
		280675 ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41		KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90
+	Hs
		318815 Q49AR9_HUMAN (40-425): 1.96e-47: 176: 18.14		K2C75_HUMAN (1-551): 1.13e-87: 285: 22.02
+	Hs
		943638 Q49AR9_HUMAN (40-425): 1.96e-47: 176: 18.14		KRT83_HUMAN (33-536): 3.41e-88: 284: 21.58
+	Hs
		318854 ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41		K2C75_HUMAN (1-551): 1.13e-87: 285: 22.02
+	Hs
		1266449 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		KRT35_HUMAN (212-560): 1.37e-09: 62.6: 10.64
+	Hs
		943653 ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41		KRT83_HUMAN (33-536): 3.41e-88: 284: 21.58
+	Hs
		1071190 Q49AR9_HUMAN (40-425): 1.96e-47: 176: 18.14		K1H1_HUMAN (105-479): 5.22e-77: 252: 37.60
+	Hs
		1071311 ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41		K1H1_HUMAN (105-479): 5.22e-77: 252: 37.60