HitPredict

Interactor 1: PAP (P29468)
Poly(A) polymerase (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase)
Gene: PAP1

Interactor 2: CFT2 (Q12102)
Cleavage factor two protein 2 (105 kDa protein associated with polyadenylation factor I)
Gene: CFT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	10523662, 11805826, 9303317, 16554755, 16429126, 37968396
Identification Methods	coimmunoprecipitation, tandem affinity purification, biochemical, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 568 Sc			1 859
+	At
		287445 PAPS2_ARATH (2-541): 0: 793: 35.46		CPSF2_ARATH (16-859): 0: 729: 21.02
+	At
		1258238 PAPS4_ARATH (1-555): 0: 785: 34.92		CPSF2_ARATH (16-859): 0: 729: 21.02
+	Hs
		843561 PAPOA_HUMAN (3-563): 0: 737: 37.43		CPSF2_HUMAN (14-859): 0: 765: 19.40
+	At
		287443 PAPS2_ARATH (2-541): 0: 793: 35.46		CPSF3_ARATH (10-471): 1.34e-153: 468: 16.98
+	At
		287442 PAPS2_ARATH (2-541): 0: 793: 35.46		CPS3B_ARATH (6-488): 1.2e-133: 413: 15.32
+	Hs
		843562 PAPOA_HUMAN (3-563): 0: 737: 37.43		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99
+	Sc
		667538 PAP_YEAST (1-568): 0: 776: 100.00		YSH1_YEAST (2-430): 2.45e-134: 421: 15.86
+	At
		1122804 PAPS3_ARATH (20-444): 0: 550: 31.24		CPS3B_ARATH (6-488): 1.2e-133: 413: 15.32