Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Interactor 2: CDT1 (P47112)
Cell division cycle protein CDT1 (SIC1 indispensable protein 2) (Topoisomerase-A hypersensitive protein 11)
Gene: TAH11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 23851460, 11836525, 16824194, 28643783, 31385807, 22045335, 23603117, 32701054, 22250202, 24234446
Identification Methods anti bait coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDT1_C~MCM, CDT1_C~MCM_lid, CDT1_C~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 868
Sc

1 604
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024