HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28162934
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 183
+	Hs
		667644 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		443291 CDK1_HUMAN (1-289): 2.35e-143: 407: 66.90		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		884317 CDK5_HUMAN (1-292): 4.84e-138: 393: 59.39		UBE2A_HUMAN (4-150): 3.11e-64: 196: 30.46
+	Hs
		970343 CDK5_HUMAN (1-292): 4.84e-138: 393: 59.39		UBE2H_HUMAN (1-183): 5.57e-64: 196: 100.00
+	Hs
		897170 CDK7_HUMAN (2-298): 9.86e-124: 359: 44.00		UB2D1_HUMAN (7-150): 3.92e-72: 215: 32.43