HitPredict

Interactor 1: SPB3 (P29508)
Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1)
Gene: SERPINB3

Interactor 2: GPR18 (Q14330)
N-arachidonyl glycine receptor (NAGly receptor) (G-protein coupled receptor 18)
Gene: GPR18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 331
+	Hs
		820307 SPB4_HUMAN (1-390): 6.25e-177: 499: 91.80		GPR18_HUMAN (1-331): 2.11e-76: 239: 100.00
+	Hs
		667920 SPB3_HUMAN (1-390): 3.74e-179: 505: 100.00		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		686612 SPB4_HUMAN (1-390): 6.25e-177: 499: 91.80		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		686769 SPB13_HUMAN (1-390): 5.91e-160: 456: 58.16		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		397010 PAI2_HUMAN (1-390): 6.23e-155: 444: 41.73		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		686619 SPB8_HUMAN (1-390): 8.05e-152: 435: 42.35		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		327732 SPB8_HUMAN (1-390): 8.05e-152: 435: 42.35		OR2H2_HUMAN (1-303): 2.74e-63: 205: 12.50
+	Hs
		344279 AACT_HUMAN (4-390): 7.56e-142: 411: 32.82		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		738755 SPB5_HUMAN (1-390): 4.3e-132: 384: 34.34		GPR18_HUMAN (1-331): 2.11e-76: 239: 100.00
+	Hs
		344168 A1AT_HUMAN (2-390): 4.63e-140: 406: 32.82		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97
+	Hs
		271853 SPB7_HUMAN (1-390): 3.38e-140: 405: 39.80		CCR1_HUMAN (8-328): 4.05e-67: 216: 20.97