Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.755

The method score is based on:

Property Details
Experiments 24637324, 19380586, 23028697, 18708055, 29180619, 21252943, 15707587, 18408734, 22388745, 24907272
Identification Methods protein complementation assay, fluorescent resonance energy transfer, enzymatic study, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 882
Hs

1 190
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Last updated: 15 Jul 2024