HitPredict

Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: ZMYM2 (Q9UBW7)
Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)
Gene: ZMYM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	25133527, 32891193, 17027752, 36880596
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0016605 - PML body GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 1377
+	Hs
		668752 PML_HUMAN (1-882): 0: 902: 100.00		ZMYM4_HUMAN (36-1377): 0: 1550: 33.76
+	Hs
		668678 PML_HUMAN (1-882): 0: 902: 100.00		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Hs
		1354409 TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56		ZMYM2_HUMAN (1-1377): 0: 1880: 100.00
+	Hs
		170501 TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49		ZMYM2_HUMAN (1-1377): 0: 1880: 100.00
+	Hs
		1029523 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		ZMYM4_HUMAN (36-1377): 0: 1550: 33.76
+	Hs
		668730 PML_HUMAN (1-882): 0: 902: 100.00		QRIC1_HUMAN (1067-1369): 2.27e-133: 431: 38.44
+	Hs
		668741 PML_HUMAN (1-882): 0: 902: 100.00		ZMYM1_HUMAN (534-876): 5.05e-60: 228: 16.44
+	Hs
		669054 PML_HUMAN (1-882): 0: 902: 100.00		ZMYM5_HUMAN (504-714): 5.85e-37: 151: 18.55