Protein: CXCR3
C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)

Gene: CXCR3
Organism: Homo sapiens
Interactions: 162
UniProt ID: P49682

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0002685 - regulation of leukocyte migration
GO:0004950 - chemokine receptor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

886048

CXCL9
C-X-C motif chemokine 9

4

20

Small-scale

0.888

High

158939

CXL11
C-X-C motif chemokine 11

3

20

Small-scale

0.814

High

390388

CXL10
C-X-C motif chemokine 10

3

20

Small-scale

0.814

High

231419

CXL13
C-X-C motif chemokine 13

1

2

Small-scale

0.647

High

390363

PLF4
Platelet factor 4

1

20

Small-scale

0.647

High

562880

CCL5
C-C motif chemokine 5

1

20

Small-scale

0.618

High

886041

CCL11
Eotaxin

1

20

Small-scale

0.618

High

886043

CXCR4
C-X-C chemokine receptor type 4

1

16

Small-scale

0.618

High

886045

CCL7
C-C motif chemokine 7

1

20

Small-scale

0.618

High

886123

CCL13
C-C motif chemokine 13

1

20

Small-scale

0.618

High

155447

C2C2L
Phospholipid transfer protein C2CD2L

2

1

High-throughput

0.606

High

886103

CLD19
Claudin-19

2

4

High-throughput

0.606

High

886157

TM14A
Transmembrane protein 14A

2

0

High-throughput

0.580

High

755535

TTK
Dual specificity protein kinase TTK

1

5

High-throughput

0.575

High

770794

HRH1
Histamine H1 receptor

1

19

High-throughput

0.575

High

886082

QSOX2
Sulfhydryl oxidase 2

1

4

High-throughput

0.575

High

886093

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

1

1

High-throughput

0.575

High

886158

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

3

High-throughput

0.575

High

628350

CD33
Myeloid cell surface antigen CD33

1

0

High-throughput

0.546

High

886115

FATE1
Fetal and adult testis-expressed transcript protein

1

1

High-throughput

0.541

High

886055

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

886056

LASP1
LIM and SH3 domain protein 1

1

5

Small-scale

0.479

High

137202

EXOC5
Exocyst complex component 5

1

2

High-throughput

0.445

High

161290

ENC1
Ectoderm-neural cortex protein 1

1

2

High-throughput

0.445

High

187488

FANCA
Fanconi anemia group A protein

1

5

High-throughput

0.445

High

190593

MRP4
ATP-binding cassette sub-family C member 4

1

7

High-throughput

0.445

High

225786

AP1G1
AP-1 complex subunit gamma-1

1

3

High-throughput

0.445

High

230771

EXTL3
Exostosin-like 3

1

2

High-throughput

0.445

High

270629

ATP9A
Probable phospholipid-transporting ATPase IIA

1

10

High-throughput

0.445

High

296910

DGAT1
Diacylglycerol O-acyltransferase 1

1

4

High-throughput

0.445

High

319525

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.445

High

320439

TM63A
Mechanosensitive cation channel TMEM63A

1

5

High-throughput

0.445

High

326932

UBE4B
Ubiquitin conjugation factor E4 B

1

4

High-throughput

0.445

High

336263

BRI3
Membrane protein BRI3

1

3

High-throughput

0.445

High

336533

PIGN
GPI ethanolamine phosphate transferase 1

1

16

High-throughput

0.445

High

603894

CXA1
Gap junction alpha-1 protein

1

10

High-throughput

0.445

High

611031

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

15

High-throughput

0.445

High

661240

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

20

High-throughput

0.445

High

722414

CTR1
High affinity cationic amino acid transporter 1

1

11

High-throughput

0.445

High

753783

MRP1
Multidrug resistance-associated protein 1

1

7

High-throughput

0.445

High

843379

HD
Huntingtin

1

4

High-throughput

0.445

High

886040

KNTC1
Kinetochore-associated protein 1

1

2

High-throughput

0.445

High

886042

ADCY7
Adenylate cyclase type 7

1

2

High-throughput

0.445

High

886046

AT2C1
Calcium-transporting ATPase type 2C member 1

1

20

High-throughput

0.445

High

886049

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

7

High-throughput

0.445

High

886050

ATM
Serine-protein kinase ATM

1

15

High-throughput

0.445

High

886051

MTX1
Metaxin-1

1

5

High-throughput

0.445

High

886052

FZD2
Frizzled-2

1

2

High-throughput

0.445

High

886053

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

3

High-throughput

0.445

High

886058

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.445

High

886060

MSMO1
Methylsterol monooxygenase 1

1

4

High-throughput

0.445

High

886061

ANO6
Anoctamin-6

1

3

High-throughput

0.445

High

886068

TM63B
Mechanosensitive cation channel TMEM63B

1

5

High-throughput

0.445

High

886069

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

8

High-throughput

0.445

High

886073

INT3
Integrator complex subunit 3

1

1

High-throughput

0.445

High

886078

BRAT1
Integrator complex assembly factor BRAT1

1

3

High-throughput

0.445

High

886079

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

13

High-throughput

0.445

High

886084

DYM
Dymeclin

1

5

High-throughput

0.445

High

886086

SETX
Probable helicase senataxin

1

1

High-throughput

0.445

High

886087

GP180
Integral membrane protein GPR180

1

4

High-throughput

0.445

High

886088

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

18

High-throughput

0.445

High

886090

ATCAY
Caytaxin

1

1

High-throughput

0.445

High

886092

DAAF5
Dynein axonemal assembly factor 5

1

5

High-throughput

0.445

High

886096

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.445

High

886097

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

6

High-throughput

0.445

High

886100

GHDC
GH3 domain-containing protein

1

1

Small-scale

0.445

High

886104

TM87A
Transmembrane protein 87A

1

8

High-throughput

0.445

High

886106

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

10

High-throughput

0.445

High

886107

ZNT7
Zinc transporter 7

1

13

High-throughput

0.445

High

886108

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

13

High-throughput

0.445

High

886112

RUFY2
RUN and FYVE domain-containing protein 2

1

5

High-throughput

0.445

High

886113

PIEZ1
Piezo-type mechanosensitive ion channel component 1

1

2

High-throughput

0.445

High

886124

NDC1
Nucleoporin NDC1

1

3

High-throughput

0.445

High

886126

STRA6
Receptor for retinol uptake STRA6

1

3

High-throughput

0.445

High

886127

TACAN
Transmembrane protein 120A

1

4

High-throughput

0.445

High

886128

YIPF3
Protein YIPF3

1

7

High-throughput

0.445

High

886130

INT2
Integrator complex subunit 2

1

3

High-throughput

0.445

High

886131

F234A
Protein FAM234A

1

1

High-throughput

0.445

High

886133

UN45A
Protein unc-45 homolog A

1

2

High-throughput

0.445

High

886134

PIGU
GPI-anchor transamidase component PIGU

1

3

High-throughput

0.445

High

886135

GOLP3
Golgi phosphoprotein 3

1

3

High-throughput

0.445

High

886138

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

15

Small-scale

0.445

High

886141

SERC1
Serine incorporator 1

1

3

High-throughput

0.445

High

886144

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.445

High

886147

ATX10
Ataxin-10

1

1

High-throughput

0.445

High

886148

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.445

High

886149

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

1

High-throughput

0.445

High

886150

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.445

High

886153

FZD1
Frizzled-1

1

2

High-throughput

0.445

High

886156

AGRG1
Adhesion G-protein coupled receptor G1

1

11

High-throughput

0.445

High

886039

PSN1
Presenilin-1

1

0

High-throughput

0.426

High

886070

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.426

High

64758

RIMC1
RAB7A-interacting MON1-CCZ1 complex subunit 1

1

1

High-throughput

0.407

High

173683

BTAF1
TATA-binding protein-associated factor 172

1

5

High-throughput

0.407

High

219287

B4GA1
Beta-1,4-glucuronyltransferase 1

1

1

High-throughput

0.407

High

244337

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.407

High

248573

FADS1
Acyl-CoA

1

8

High-throughput

0.407

High

252842

EXOC3
Exocyst complex component 3

1

4

High-throughput

0.407

High

273173

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

12

High-throughput

0.407

High

295729

AP1G2
AP-1 complex subunit gamma-like 2

1

3

High-throughput

0.407

High

301369

WFS1
Wolframin

1

2

High-throughput

0.407

High

341241

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

1

High-throughput

0.407

High

399670

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

6

High-throughput

0.407

High

506578

GPHRB
Golgi pH regulator B

1

10

High-throughput

0.407

High

814767

CUX1
Homeobox protein cut-like 1

1

8

High-throughput

0.407

High

877302

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

High-throughput

0.407

High

886044

AP1S1
AP-1 complex subunit sigma-1A

1

4

High-throughput

0.407

High

886047

KDSR
3-ketodihydrosphingosine reductase

1

5

High-throughput

0.407

High

886054

COG2
Conserved oligomeric Golgi complex subunit 2

1

3

High-throughput

0.407

High

886057

TRAM2
Translocating chain-associated membrane protein 2

1

16

High-throughput

0.407

High

886059

UBE3C
Ubiquitin-protein ligase E3C

1

8

High-throughput

0.407

High

886062

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

10

High-throughput

0.407

High

886063

YIF1B
Protein YIF1B

1

4

High-throughput

0.407

High

886064

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

1

16

High-throughput

0.407

High

886065

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

2

High-throughput

0.407

High

886066

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.407

High

886067

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

2

High-throughput

0.407

High

886071

TBC9B
TBC1 domain family member 9B

1

3

High-throughput

0.407

High

886072

ZFY26
Zinc finger FYVE domain-containing protein 26

1

7

High-throughput

0.407

High

886074

RINT1
RAD50-interacting protein 1

1

4

High-throughput

0.407

High

886075

D19L2
Probable C-mannosyltransferase DPY19L2

1

2

High-throughput

0.407

High

886076

TTI2
TELO2-interacting protein 2

1

3

High-throughput

0.407

High

886077

ZNT6
Zinc transporter 6

1

13

High-throughput

0.407

High

886080

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

4

High-throughput

0.407

High

886081

LCLT1
Lysocardiolipin acyltransferase 1

1

7

High-throughput

0.407

High

886083

DPH6
Diphthine--ammonia ligase

1

2

High-throughput

0.407

High

886085

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

6

High-throughput

0.407

High

886089

RETR3
Reticulophagy regulator 3

1

7

High-throughput

0.407

High

886091

CNDG2
Condensin-2 complex subunit G2

1

2

High-throughput

0.407

High

886094

ZDH13
Palmitoyltransferase ZDHHC13

1

7

High-throughput

0.407

High

886095

ZDH17
Palmitoyltransferase ZDHHC17

1

8

High-throughput

0.407

High

886098

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

5

High-throughput

0.407

High

886099

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

5

High-throughput

0.407

High

886101

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

1

High-throughput

0.407

High

886102

CERS5
Ceramide synthase 5

1

16

High-throughput

0.407

High

886105

RETR2
Reticulophagy regulator 2

1

7

High-throughput

0.407

High

886109

SFXN5
Sideroflexin-5

1

7

High-throughput

0.407

High

886110

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

16

High-throughput

0.407

High

886111

COG1
Conserved oligomeric Golgi complex subunit 1

1

2

High-throughput

0.407

High

886114

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.407

High

886116

TM186
Transmembrane protein 186

1

1

High-throughput

0.407

High

886117

INT12
Integrator complex subunit 12

1

4

High-throughput

0.407

High

886118

YIPF6
Protein YIPF6

1

2

High-throughput

0.407

High

886119

TM101
Transmembrane protein 101

1

1

High-throughput

0.407

High

886121

MIA2
Melanoma inhibitory activity protein 2

1

3

High-throughput

0.407

High

886122

PIGS
GPI-anchor transamidase component PIGS

1

1

High-throughput

0.407

High

886125

PTSS2
Phosphatidylserine synthase 2

1

8

High-throughput

0.407

High

886132

TM245
Transmembrane protein 245

1

1

High-throughput

0.407

High

886137

AT133
Polyamine-transporting ATPase 13A3

1

20

High-throughput

0.407

High

886142

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

8

High-throughput

0.407

High

886143

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.407

High

886145

T161A
Transmembrane protein 161A

1

5

High-throughput

0.407

High

886146

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

3

High-throughput

0.407

High

886151

IPO11
Importin-11

1

11

High-throughput

0.407

High

886152

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

11

High-throughput

0.407

High

886154

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

5

High-throughput

0.407

High

886155

FADS3
Fatty acid desaturase 3

1

8

High-throughput

0.407

High

886120

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

0

High-throughput

0.232

Low

886129

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.232

Low

886136

TRABD
TraB domain-containing protein

1

0

High-throughput

0.232

Low

886139

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.232

Low

886140

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025