Protein: PIEZ1
Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)

Gene: PIEZ1, PIEZO1
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q92508

Gene Ontology (top 5):
GO:0005261 - monoatomic cation channel activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006812 - monoatomic cation transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

967332

TSN5
Tetraspanin-5

3

2

High-throughput

0.667

High

1363519

YIPF3
Protein YIPF3

2

0

High-throughput

0.602

High

480868

LEG1
Galectin-1

2

2

High-throughput

0.601

High

609761

LEG3
Galectin-3

2

2

High-throughput

0.601

High

956960

CXCR4
C-X-C chemokine receptor type 4

2

2

High-throughput

0.601

High

170898

CLGN
Calmegin

2

0

High-throughput

0.576

High

1242884

S39A4
Zinc transporter ZIP4

2

0

High-throughput

0.576

High

1363526

FBX2
F-box only protein 2

2

0

High-throughput

0.576

High

396614

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

174020

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.536

High

252616

TSN2
Tetraspanin-2

1

2

High-throughput

0.536

High

349509

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

669043

FPR2
N-formyl peptide receptor 2

1

2

High-throughput

0.536

High

851190

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.536

High

901437

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.536

High

1363514

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.536

High

1363528

GPR55
G-protein coupled receptor 55

1

1

High-throughput

0.536

High

720426

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

1

High-throughput

0.515

High

125039

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

706041

CXB2
Gap junction beta-2 protein

1

0

High-throughput

0.513

High

800308

INGR2
Interferon gamma receptor 2

1

0

High-throughput

0.513

High

900957

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.513

High

963966

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.513

High

1203752

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1328488

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.513

High

1363520

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1363524

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1363529

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1363531

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.513

High

125547

LEG9
Galectin-9

1

2

High-throughput

0.489

High

1363521

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

218555

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

1358321

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.458

High

1363518

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.458

High

886113

CXCR3
C-X-C chemokine receptor type 3

1

2

High-throughput

0.445

High

1363513

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1363525

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.437

High

230995

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.426

High

704054

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.426

High

1033936

SC6A3
Sodium-dependent dopamine transporter

1

0

High-throughput

0.426

High

1093560

TRDN
Triadin

1

0

High-throughput

0.426

High

1236250

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1244106

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

1355913

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.426

High

1363517

S1PR3
Sphingosine 1-phosphate receptor 3

1

0

High-throughput

0.426

High

1363522

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.426

High

1363523

SCN3B
Sodium channel regulatory subunit beta-3

1

0

High-throughput

0.426

High

1363527

FZD10
Frizzled-10

1

0

High-throughput

0.426

High

1239024

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.407

High

1242184

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.407

High

1248306

CP20A
Cytochrome P450 20A1

2

0

High-throughput

0.319

High

1177851

CL12B
C-type lectin domain family 12 member B

2

0

High-throughput

0.313

High

1229929

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

1363515

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1363516

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.279

Low

1363532

DMRT1
Doublesex- and mab-3-related transcription factor 1

1

0

High-throughput

0.279

Low

404608

TFF1
Trefoil factor 1

1

0

Small-scale

0.276

Low

1363530

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

419111

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.249

Low

702638

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.249

Low

1175884

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.232

Low

1219525

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low

1308920

S22A9
Organic anion transporter 7

1

0

High-throughput

0.232

Low

1337886

ZNT7
Zinc transporter 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025